Name

KUGOH Hiroyuki

Affiliation

Faculty of Medicine , School of Life Science , Department of Chromosome Biomedical Engineering

Title

Professor

Web Site

https://saiboukougaku.jimdofree.com

Research areas, keyword

tumor suppressor genes, chromosome engineering, imprinting, epigenetics

Research Achievement (Published Thesis)

• Human artificial chromosome carrying 3p21.3-p22.2 region suppresses hTERT transcription in oral cancer cells. , Ohira T, Yoshimura K, Kugoh H , Chromosome Res. , vol.31 (3) (p.17 - ) , 2023.08 , There is Review , The Multiple Authorship , English

• Locus-specific induction of gene expression from heterochromatin loci during cellular senescence. , 72. Tomimatsu K, Bihary D, Olan I, Parry AJ, Schoenfelder S, Chan ASL, Slater GStC, Ito Y, Rugg-Gunn PJ, Kirschner K, Bermejo-Rodriguez C, Seko T, Kugoh H, Shiraishi K, Sayama K, Kimura H, Fraser P, Narita M, Samarajiwa SA, Narita M. , Nature Aging , vol.2 (1) (p.31 - 45) , 2022.01 , There is Review , The Multiple Authorship , English

• Human chromosome 3p21.3 carries TERT transcriptional regulators in pancreatic cancer. , 70. Yagyu T, Ohira T, Shimizu R, Morimoto M, Murakami Y, Hanaki T, Kihara K, Matsunaga T, Yamamoto M, Tokuyasu N, Sakamoto T, Fujiwara Y, *Kugoh H. , Sci Rep. , vol.11 (1) (p.15355 - ) , 2021.07 , There is Review , The Multiple Authorship , English

• CGG repeat RNA G-quadruplexes interact with FMRpolyG to cause neuronal dysfunction in fragile X-related tremor/ataxia syndrome, , Asamitsu S, Yabuki Y, Ikenoshita S, Kawakubo K, Kawasaki M, Usuki S, Nakayama Y, Adachi K, Kugoh H, Ishii K, Matsuura T, Nanba E, Sugiyama H, Fukuanga K, Shioda N. , Science Advances, , vol.7 (3) (p.eabd9440 - ) , 2021.01 , The Multiple Authorship , English

• Real-time fluorometric evaluation of hepatoblast proliferation in vivo and in vitro using the expression of CYP3A7 coding for human fetus-specific P450. , Okuyama S, Kawamura F, Kubiura M, Tsuji S, Osaki M, Kugoh H, Oshimura M, Kazuki Y, Tada M. , Pharmacology Research & Perspectives, , vol.8 (5) (p.e00642 - ) , 2020.10 , The Multiple Authorship , English

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Research Achievement (Review)

• ゲノムインプリンティング-核内におけるインプリント遺伝子の発現動態- , 片岡美喜、久郷裕之 , 生体の科学 , 　　 , vol.68 (3) (p.209 - 214) , 2017 , 片岡美喜、久郷裕之 , Learned Journal , The Multiple Authorship , English

• Identification of PITX1 as a TERT suppressor gene located on human chromosome 5.・がん細胞増殖防ぐ遺伝子 , 久郷裕之 , Mol. Cellular Bio., 読売新聞 , 　 , vol.31 (8) (p.1624 - 1636) , 2011 , 久郷裕之 , Others , The Multiple Authorship , English

• Identification of PITX1 as a TERT suppressor gene located on human chromosome 5.・今日の人物 , 久郷裕之 , Mol. Cell Biol・ジャパンナレッジ , 　 , vol.31 (8) (p.1624 - 1636) , 2011 , 久郷裕之 , Others , The Multiple Authorship , English

• Identification of the chromatin regions coated by non-coding Xist RNA・長鎖ncRNAが操る「生命現象の裏社会」 , 久郷裕之 , Cytogenetic and Genome Research・Nature Japan , 　 , vol.125 (1) (p.19 - 25) , 2009 , 久郷裕之 , Others , The Multiple Authorship , English

Updated on 2025/08/14