Name

TSUCHIYA Hiroyuki

Affiliation

Faculty of Medicine , School of Medicine , Division of Regenerative Medicine and Therapeutics

Title

Associate Professor

Research areas, keyword

liver diseases

School Attended (except graduate school)

• Hokkaido University , Faculty of Pharmaceutical Science , 2000.03 , Graduated , JAPAN

Graduate School Attended, etc.

• Hokkaido University , Graduate School, Division of Pharmaceutical Sciences , 2002.03 , Completed , JAPAN

• Hokkaido University , Graduate School, Division of Pharmaceutical Sciences , 2005.03 , Completed , JAPAN

Degree

• Ph.D. , Hokkaido University , Coursework , 2005.03

Acquisition qualification

• Pharmacist

External Career

• Assistant Professor , 2005.04 - 2010.03

• Lecturer , 2010.04 - 2012.12

• Researcher , 2013.01 - 2014.09

Research Field (grants-in-aid-for-scientific-research classification)

• Digestive organs internal medicine

• Biological system pharmaceutical science

Research Achievement (Published Thesis)

• NEAT1 is Required for the Expression of the Liver Cancer Stem Cell Marker CD44. , Shigemi Koyama, Hiroyuki Tsuchiya, Masataka Amisaki, Hiromi Sakaguchi, Soichiro Honjo, Yoshiyuki Fujiwara, Goshi Shiota. , International Journal of Molecular Sciences , vol.21 (6) (p.1927 - ) , 2020.03 , There is Review , The Multiple Authorship , English

• WNT/β-catenin signal inhibitor IC-2–derived small-molecule compounds suppress TGF-β1–induced fibrogenic response of renal epithelial cells by inhibiting SMAD2/3 signaling. , Shotaro Hoi, Hiroyuki Tsuchiya, Noriko Itaba, Kyosuke Suzuki, Hiroyuki Oka, Minoru Morimoto, Tomoaki Takata, Hajime Isomoto, Goshi Shiota. , Clin Exp Pharmacol Physiol , 2020 , There is Review , The Multiple Authorship , English

• Identification of genes involved in the regulation of Telomerase Reverse Transcriptase in hepatocellular carcinoma. , Masataka Amisaki, Hiroyuki Tsuchiya, Tomohiko Sakabe, Yoshiyuki Fujiwara, Goshi Shiota. , Cancer Sci , vol.2 (p.550 - 560) , 2019 , There is Review , The Multiple Authorship , English

• No enhancing effects of plasmid-specific histone acetyltransferase recruitment system on transgene expression in vivo. , Tetsuya Suzuki, Yusuke Wakao, Tadashi Watanabe, Mika Hori, Yoshito Ikeda, Hiroyuki Tsuchiya, Kentaro Kogure, Mariko Harada-Shiba, Masahiro Fujimuro, Hiroyuki Kamiya. , Nucleosides Nucleotides Nucleic Acids , vol.38 (p.942 - 949) , 2019 , There is Review , The Multiple Authorship , English

• CD44 standard isoform is involved in maintenance of cancer stem cells of a hepatocellular carcinoma cell line. , Ryoma Asai, Hiroyuki Tsuchiya, Masataka Amisaki, Kazuki Makimoto, Ai Takenaga, Tomohiko Sakabe, Shotaro Hoi, Shigemi Koyama, Goshi Shiota. , Cancer Med , vol.8 (p.773 - 782) , 2019 , There is Review , The Multiple Authorship , English

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Research Achievement (Review)

• NEAT1–SOD2 Axis Confers Sorafenib and Lenvatinib Resistance by Activating AKT in Liver Cancer Cell Lines. , Hiroyuki Tsuchiya, Ririko Shinonaga, Hiromi Sakaguchi, Yutaka Kitagawa, Kenji Yoshida. , Current Issues in Molecular Biology , MDPI , vol.45 (2) (p.1073 - ) , 2023.01 , Hiroyuki Tsuchiya, Ririko Shinonaga, Hiromi Sakaguchi, Yutaka Kitagawa, Kenji Yoshida. , Learned Journal , The Multiple Authorship , English

• NEAT1 confers radioresistance to hepatocellular carcinoma cells by inducing PINK1/parkin-mediated mitophagy. , Hiroyuki Tsuchiya, Ririko Shinonaga, Hiromi Sakaguchi, Yutaka Kitagawa, Kenji Yoshida, Goshi Shiota. , International Journal of Molecular Sciences , MDPI , vol.23 (22) (p.14397 - ) , 2022.11 , Hiroyuki Tsuchiya, Ririko Shinonaga, Hiromi Sakaguchi, Yutaka Kitagawa, Kenji Yoshida, Goshi Shiota. , Learned Journal , The Multiple Authorship , English

• Iron-Induced Hepatocarcinogenesis—Preventive Effects of Nutrients , Hiroyuki Tsuchiya , Frontiers in Oncology , Frontiers Media S.A. , vol.12 (p.940552 - ) , 2022.06 , Hiroyuki Tsuchiya , Learned Journal , The Simple Work , English

• NEAT1 Confers Radioresistance to Hepatocellular Carcinoma Cells by Inducing Autophagy through GABARAP. , Hiromi Sakaguchi, Hiroyuki Tsuchiya, Yutaka Kitagawa, Tomohiko Tanino, Kenji Yoshida, Nobue Uchida, Goshi Shiota. , International Journal of Molecular Sciences , MDPI , vol.23 (2) (p.711 - ) , 2022.01 , Hiromi Sakaguchi, Hiroyuki Tsuchiya, Yutaka Kitagawa, Tomohiko Tanino, Kenji Yoshida, Nobue Uchida, Goshi Shiota. , Learned Journal , The Multiple Authorship , English

• Immune evasion by cancer stem cells , Hiroyuki Tsuchiya, Goshi Shiota , Regenerative Therapy , Elsevier B.V. , vol.17 (p.20 - 33) , 2021.03 , Hiroyuki Tsuchiya, Goshi Shiota , Learned Journal , The Multiple Authorship , English

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Updated on 2023/02/24