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Tbx18-positive cells differentiated from murine ES cells serve as proepicardial progenitors to give rise to vascular smooth muscle cells and fibroblasts. , Ikeda N, Nakazawa N, Kurata Y, Yaura H, Taufiq F, Minato H, Yoshida A, Ninomiya H, Nakayama Y, Hisatome I , Biomed. Res. , vol.38 (p.229 - 238) , 2017 , There is Review , The Multiple Authorship , English
Endoplasmic reticulum-associated degradation of Niemann-Pick C1: evidence for the role of heat shock proteins and identification of lysine residues that accept ubiquitin. (共著） , Nakasone N., Yuko S.N., Higaki K., Oumi N., Ohno K. and Ninomiya H. , J. Biol. Chem , vol.289 (p.19714 - 19725) , 2014 , There is Review , The Multiple Authorship , English
Chaperone activity of bicyclic nojirimycin analogues for Gaucher mutations in comparison with N-(n-nonyl)deoxynojirimycin. , Luan Z., Higaki K., Aguilar-Moncayo M., Ninomiya H., Ohno K., Garcia-Moreno M.I., Ortiz Mellet C., Garcia Fernandez J.M. and Suzuki Y. , Chembiochem. , vol.23 (0) (p.2780 - 2792) , 2009 , There is Review , The Multiple Authorship , English
Niemann-Pick C1 protein transports copper to the secretory compartment from late endosomes where ATP7B resides. , Yanagimoto C., Harada M., Kumemura H., Koga H., Kawaguchi T., Terada K., Hanada S., Taniguchi E., Koizumi Y., Koyota S., Ninomiya H., Ueno T., Sugiyama T. and Sata M. , Exp. cell Res. , vol.315 (0) (p.119 - 126) , 2009 , There is Review , The Multiple Authorship , English
Brainstem neuropathology in a mouse model of Niemann-Pick disease type C. , Luan Z., Saito Y., Miyata H., Ohama E., Ninomiya H. and Ohno K. , J. Neurol. Sci , vol.268 (0) (p.108 - 116) , 2008 , There is Review , The Multiple Authorship , English
Enhanced autophagy and mitochondrial aberrations in murine GM1-gagliosidosis. , Takamura A., Higaki K., Kajimaki K., Otsuka S., Ninomiya H., Matsuda J., Ohno K., Suzuki Y. and Nanba E. , Biochem. Biophys. Res. Commun. , vol.367 (0) (p.616 - 622) , 2008 , There is Review , The Multiple Authorship , English
Endosomal accumulation of Toll-like receptor 4 causes constitutive secretion of cytokines and activation of signal transducers and activators of transcription in Niemann-Pick disease type C (NPC) fibroblasts: a potential basis for glial cell activation in the NPC brain. , 8. Suzuki M., Sugimoto Y., Ohsaki Y., Ueno M., Kato S., Kitamura Y., Hosokawa H., Davies J.P., Ioannou Y.A., Vanier M.T., Ohno K. and Ninomiya H. , J. Neurosci. , vol.27 (0) (p.1879 - 1891) , 2007 , There is Review , The Multiple Authorship , English
The TSC1 gene product hamartin interacts with NADE. , 4. Yasui S., Tsuzaki K., Ninomiya H., Floricel F., Asano S., Maki H., Takamura A., Nanba E. Higaki K. and Ohno K. , Mol. Cell. Neurosci. , vol.35 (0) (p.100 - 108) , 2007 , There is Review , The Multiple Authorship , English
Serum levels of uridine correlate with blood pressure and indicators of myogenic purine degradation, anaerobic glycolysis and insulin resistance in hypertensive patients. , 7. Hamada T., Mizuta E., Yanagihara K., Kato M., Igawa O., Inokuchi T., Yamamoto T., Shimada T., Ninomiya H., Yamamoto Y. and Hisatome I. , Circ. J. , vol.71 (0) (p.354 - 356) , 2007 , There is Review , The Multiple Authorship , English
Antisense suppression of TSC1 gene product, hamartin enhances neurite outgrowth in NGF-treated PC12h cells. , 3. Floricel F., Higaki K., Maki M., Nanba E., Ninomiya H. and Ohno K. , Brain Dev. , vol.29 (0) (p.502 - 509) , 2007 , There is Review , The Multiple Authorship , English
Amyloid beta inhibits ectodomain shedding of N-cadherin via down-regulation of cell-surface NMDA receptor. , 9. Uemura K., Kuzuya A., Aoyagi N., Ando K., Shimozono Y., Ninomiya H., Shimohama S. and Kinoshita A. , Neuroscience , vol.145 (0) (p.5 - 10) , 2007 , There is Review , The Multiple Authorship , English
Remote reperfusion lung injury is associated with AMP deaminase 3 activation and attenuated by inosine monophosphate. , 6. Li P., Ogino K., Hoshikawa Y., Morisaki H., Cheng J., Toyama K., Morisaki T., Hashimoto K., Ninomiya H., Tomikura-Shimoyama Y., Igawa O., Shigemasa C. and Hisatome I. , Circ J. , vol.71 (0) (p.591 - 596) , 2007 , There is Review , The Multiple Authorship , English
Presenilin 1 is involved in the maturation of beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1). , 10. Kuzuya A., Uemura K., Kitagawa N., Aoyagi N., Kihara T., Ninomiya H., Ishiura S., Takahashi R. and Shimohama S. , J. Neurosci. Res. , vol.85 (0) (p.153 - 165) , 2007 , There is Review , The Multiple Authorship , English
Mental retardation, spasticity, basal ganglia calcification, cerebral white matter lesions, multiple endocrine defects, telangiectasia and atrophic skin: A new syndrome? , Saito Y., Toyoshima M., Oka A., Luan Z., Moriwaki S., Yamamoto O., Kanzaki S., Hanaki K., Ninomiya H., Nanaba E., Kondo A., Maegaki Y. and Ohno K. , Brain Dev. , vol.in press (0) (p.0) , 2007 , There is Review , The Multiple Authorship , English
Inhibition of beta-adrenergic signaling by intracellular AMP is independent of cell-surface adenosine receptors in rat cardiac cells. , 1. Ogura K., Miake J., Sasaki N., Iwai C., Bahrudin U., Li P., Kato M., Iitsuka K., Hirota Y., Koshida T., Yamamoto Y., Inoue Y., Yano A., Adachi M., Igawa O., Kurata Y., Morisaki T., Shiota G., Shirayoshi Y., Ninomiya H. and Hisatome I. , J. Mol. Cell. Cardiol. , vol.43 (0) (p.648 - 652) , 2007 , There is Review , The Multiple Authorship , English
Enzyme enhancement activity of N-octyl-beta-valienamine on beta-glucosidase mutants associated with Gaucher disease. , 5. Lei K., Ninomiya H., Suzuki M., Inoue T., Sawa M., Iida M., Ida H., Eto Y., Ogawa S., Ohno K. and Suzuki Y. , Biochim. Biophys. Acta , vol.1772 (0) (p.587 - 596) , 2007 , There is Review , The Multiple Authorship , English
Cholesterol depletion facilitates ubiquitylation of NPC1 and its association with SKD1/Vps4. , 13. Ohsaki Y., Sugimoto Y., Suzuki M., Hosokawa H., Yoshimori T., Davies J.P., Ioannou Y.A., Vanier M.T., Ohno K. and Ninomiya H. , J. Cell Sci. , vol.199 (0) (p.2643 - 2653) , 2006 , There is Review , The Multiple Authorship , English
Niemann-Pick type C disease: Novel NPC1 mutations and characterization of the concomitant acid sphingomyelinase deficiency. , 16. Tamura H., Takahashi T., Ban N., Torisu H., Ninomiya H., Takada G. and Inagaki N. , Mol. Genet. Metab. , vol.87 (0) (p.113 - 121) , 2006 , There is Review , The Multiple Authorship , English
Inhibition of inward rectifier K+ currents by angiotensin II in rat atrial myocytes: lack of effects in cells from spontaneous hypertensive rats. , 11. Sonoyma K., Ninomiya H., Igawa O., Miake J., Li P., Yamamoto Y., Ogino K., Yoshida A., Taniguchi S., Kurata Y., Matsuoka S., Narahashi T., Shiota G., Nozawa Y., Matubara H., Horiuchi M., Shirayoshi Y. and Hisatome I. , Hypertension Res. , vol.29 (0) (p.923 - 934) , 2006 , There is Review , The Multiple Authorship , English
Characterization of sequential N-cadherin cleavage by ADAM10 and PS1. , 15. Uemura K., Kihara T., Kuzuya A., Okawa K., Nishimoto T., Ninomiya H., Sugimoto H., Kinoshita A. and Shimohama S. , Neurosci. Lett. , vol.402 (0) (p.278 - 283) , 2006 , There is Review , The Multiple Authorship , English
Delayed onset of beating and decreased expression of T-type Ca2+ channel in mouse ES cell-derived cardiocytes carrying human chromosome 21. , 12. Mizuta E., Furuichi H., Kazuki Y., Miake J., Yano S., Bahrudin, U., Yamamoto, Y., Igawa O., Shigemasa, C., Hidaka, K., Morisaki, T., Kurata, Y., Ninomiya, H., Kitakaze M., Shirayoshi, Y., Oshimura, M. and Hisatome, I. , Biochem. Biophys. Res. Commun. , vol.351 (0) (p.126 - 132) , 2006 , There is Review , The Multiple Authorship , English
Mutation at the cleavage site of IGF receptor in short stature children born with intrauterine growth retardation. , 17. Kawashima Y., Kanzaki S., Yang F., Kinoshita T., Hanaki K., Nagaishi J.I., Ohtsuka Y., Hisatome I., Ninomiya H., Nanba E., Fukushima T. and Takahashi S.I. , J. Clin. Endocrinol. Metab. , vol.90 (0) (p.4679 - 4687) , 2005 , There is Review , The Multiple Authorship , English
The Wilson disease protein ATP7B resides in the late endosomes with Rab7 and the Niemann-Pick C1 protein. , 22. Harada M., Kawaguchi T., Kumemura H., Terada K., Ninomiya H., Taniguchi E., Hanada S., Maeyama M., Koga H., Ueno T., Furuta K., Suganuma T., Sugiyama T. and Sata M. , Am. J. Pathol. , vol.166 (0) (p.499 - 510) , 2005 , There is Review , The Multiple Authorship , English
Subtype switch of T-type Ca2+ channels from Cav3.1 to Cav3.2 during differentiation of embryonic stem cells to cardiac lineage cells. , 19. Mizuta E., Miake J., Yano S., Furuichi H., Manabe K., Igawa O., Hoshiakwa Y., Nanba E., Ninomiya H., Morisaki T. and Hisatome I. , Cir. J. , vol.69 (0) (p.1284 - 1289) , 2005 , There is Review , The Multiple Authorship , English
Proteasomal degradation of Kir6.2 channel protein and its inhibition by a Na+ channel blocker aprindine. , 21. Tanaka H., Miake J., Notsu T., Sonyama K, Sasaki N., IItsuka K., Kato M., Taniguchi S., Igawa O., Yoshida A., Shigemasa C., Hoshikawa H., Kurata Y., Kuniyasu A., Nakayama H., Inagaki N., Nanba E., Shiota G., Morisaki T., Ninomiya H., Kitakaze M. and Hisatome I. , Biochem. Biophys. Res. Commun. , vol.331 (0) (p.1001 - 1006) , 2005 , There is Review , The Multiple Authorship , English
Evidence for proteasomal degradation of Kv1.5 channel protein. , 18. Kato M., Ogura K., Miyake J., Sasaki N., Taniguchi S., Igawa O., Yoshida A., Shigemasa C., Murata M., Nanba E., Kurata Y., Morisaki T., Ninomiya H. and Hisatome I. , Biochem. Biophys. Res. Commun. , vol.337 (0) (p.343 - 348) , 2005 , There is Review , The Multiple Authorship , English
Effects of angiotensin II on the action potential durations of atrial myocytes in hypertensive rats. , 20. Sonoyama K., Igawa O., Miake J., Yamamoto Y., Sugihara S., Sasaki N., Shimoyama M., Hamada T., Taniguchi S., Yoshida A., Ogino K., Shigemasa C., Kurata Y., Shiota G., Narahashi T., Horiuchi M., Matsubara H., Ninomiya H. and Hisatome I. , Hypertension Res. , vol.28 (0) (p.173 - 179) , 2005 , There is Review , The Multiple Authorship , English
1H, 13C and 15N assignments of the tandem WW domains of human MAGI-1/BAP-1. , Kato Y., Akai A., Suzuki R., Hosokawa H., Ninomiya H., Masaki T., Nagata K. and Tanokura M. , J. Biomol. NMR , vol.29 (0) (p.539 - 540) , 2004 , There is Review , The Multiple Authorship , English
Reduced sensitivity of Niemann-Pick C1-deficient cells to theta-toxin (perfringolysin O): sequestration of toxin to raft-enriched membrane vesicles. , Ohsaki Y., Sugimoto Y., Suzuki M., Kaidoh T., Shimada Y., Ohno-Iwashita Y., Davies J.P., Ioannou Y.A., Ohno K. and Ninomiya H. , Histochem. Cell Biol. , vol.121 (0) (p.263 - 272) , 2004 , There is Review , The Multiple Authorship , English
Novel TSC2 mutations and decreased expression of tuberin in cultured tumor cells with an insertion mutation. , Feng J.H., Yamamoto T., Nanba E., Ninomiya H., Oka A., and Ohno K. , Hum. Mutat. , vol.24 (0) (p.397) , 2004 , There is Review , The Multiple Authorship , English
Novel amyloid precursor protein gene missense mutation (D678N) in probable familial Alzheimer’s disease. , Wakutani Y., Watanabe K., Adachi Y., Wada-Isoe K., Urakami K., Ninomiya H., Saido T.C., Hashimoto T., Iwatsubo T. and Nakashima K. , J. Neurol. Neurosurg. Psychiatry , vol.75 (0) (p.1039 - 1042) , 2004 , There is Review , The Multiple Authorship , English
N-Octyl-beta-valienamine up-regulates activity of F213I mutant beta-glucosidase in cultured cells: a potential chemical chaperone therapy for Gaucher disease. , Hou L., Sugimoto Y., Ohsaki Y., Ninomiya H., Oka A., Taniguchi M., Ida H., Eto Y., Ogawa S., Matsuzaki Y., Sawa M., Inoue T., Higaki K., Nanba E., Ohno K. and Suzuki Y. , Biochim. Biophys. Acta , vol.1689 (0) (p.219 - 228) , 2004 , There is Review , The Multiple Authorship , English
Increased NPC1 mRNA in skin fibroblasts from Niemann-Pick disease type C patients. , Yamamoto T., Feng J.H., Higaki K., Taniguchi M., Nanba E., Ninomiya H. and Ohno K. , Brain Dev. 26, 245-250. , vol.26 (0) (p.245 - 250) , 2004 , There is Review , The Multiple Authorship , English
Degeneration of cholecystokinin-immunoreactive afferents to the VPL thalamus of the mouse model of Niemann-Pick type C. , Ohara S., Ukita Y., Ninomiya H. and Ohno K. , Brain Res. 1022, 244-246. , vol.1022 (0) (p.244 - 246) , 2004 , There is Review , The Multiple Authorship , English
Axonal dystrophy of dorsal root ganglion sensory neurons in a mouse model of Niemann-Pick disease type C. , Ohara S., Ukita Y., Ninomiya H. and Ohno K. , Exp. Neurol. , vol.187 (0) (p.289 - 298) , 2004 , There is Review , The Multiple Authorship , English
New GAA mutations in Japanese patients with GSDII (pompe disease). , Pipo J.R., Feng J.H., Yamamoto T., Ohsaki Y., Nanba E., Tsujino S., Sakuragawa N., Martiniuk F., Ninomiya H., Oka A. and Ohno K. , Pediatr Neurol. , vol.29 (0) (p.284 - 287) , 2003 , There is Review , The Multiple Authorship , English
Smad expression of hepatic satellite cells in liver cirrhosis in vivo and hepatic satellite cell lines in vitro. , Kitamura Y and Ninomiya H , Pathol. Int. , vol.53 (0) (p.18 - 26) , 2003 , There is Review , The Multiple Authorship , English
Biotinylated -toxin derivative as a probe to examine intracellular cholesterol-rich domains in normal and Niemann-Pick type C1 cells. , Sugii S., Reid P.C., Ohgami N., Shimada Y., Maue R.A., Ninomiya H., Ohno-Iwashita Y. and Chang T.Y. , J. Lipid Res. , vol.44 (0) (p.1033 - 1041) , 2003 , There is Review , The Multiple Authorship , English
Structural basis of GM2 gangliosidosis B variant. , Matsuzawa F., Aikawa S.I., Sakuraba H., Tanaka A., Ohno K., Ninomiya H., Sugimoto Y. and Doi H. , J. Hum. Genet. , vol.42 (0) (p.582 - 589) , 2003 , There is Review , The Multiple Authorship , English
Novel TSC1 and TSC2 mutations in Japanese patients with tuberous sclerosis complex. , Yamamoto T, Pipo JR, Feng JH, Takeda H, Nanba E, Ninomiya H, and Ohno K , Brain Dev. , vol.24 (0) (p.227 - 230) , 2002 , There is Review , The Multiple Authorship , English
Vascular endothelial cells that express dystroglycan are involved in angiogenesis. , Hosokawa H., Ninomiya H., Kitamura Y., Fujiwara K. and Masaki T , J. Cell Sci. , vol.115 (0) (p.1487 - 1496) , 2002 , There is Review , The Multiple Authorship , English
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