Name

KAZUKI Yasuhiro

Affiliation

Faculty of Medicine , School of Life Science , Department of Chromosome Biomedical Engineering

Title

Professor

Research areas, keyword

Research Achievement (Published Thesis)

• Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy. , Beneditti Sara, Uno Narumi, Hoshiya Hidetoshi, Ragazzi Martina, Ferrari Giulia, Kazuki Yasuhiro, Katoh Motonobu, Kazuki Kanako, Oshimura Mitsuo, Tedesco Francesco Saverio,他 , EMBO Molecular Medicine , vol.10 (2) (p.254 - 275) , 2017.12 , There is Review , The Multiple Authorship , English

• Gender difference of hepatic and intestinal CYP3A4 in CYP3A-humanized mice generated by a human chromosome-engineering technique. , Kobayashi Kaoru, Abe Chisato, Endo Mika, Kazuki Yasuhiro, Oshimura Mitsuo, Chiba Kan , Drug Metab Lett. , vol.11 (1) (p.60 - 67) , 2017.11 , There is Review , The Multiple Authorship , English

• Modification of single-nucleotide polymorphism in a fully humanized CYP3A mouse by genome editing technology. , Abe Satoshi, Kazuki Yasuhiro,他 , Sci Rep. , vol.7 (1) , 2017.11 , There is Review , The Multiple Authorship , English

• Establishment of a novel hepatocyte model that expresses four cytochrome P450 genes stably via mammalian-derived artificial chromosome for pharmacokinetics and toxicity studies. , Satoh Daisuke, Iwado Satoru, Abe Satoshi, Kazuki Kanako, Wakuri Shinobu, Oshimura Mitsuo, Kazuki Yasuhiro , PLoS One. , vol.12 (10) , 2017.10 , There is Review , The Multiple Authorship , English

• Transfer of a Mouse Artificial Chromosome into Spermatogonial Stem Cells Generates Transchromosomic Mice. , Shinohara Takashi, Kazuki Yasuhiro,他 , Stem Cell Reports. , vol.9 (4) , 2017.10 , There is Review , The Multiple Authorship , English

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Research Achievement (Review)

• Combinations of chromosome transfer and genome editing for the development of cell/animal models of human disease and humanized animal models. , 宇野　愛海、阿部　智志、押村　光雄、香月　康宏 , Journal Of Human Genetics , 　　 , vol.63 (2) (p.145 - 156) , 2017.11 , 宇野　愛海、阿部　智志、押村　光雄、香月　康宏 , Learned Journal , The Simple Work , English

• A pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challenges. , Oshimura M, Uno N, Kazuki Y, Katoh M, Inoue T. , Chromosome Res. , KLUWER , vol.23 (1) (p.111 - 133) , 2015.02 , Oshimura M, Uno N, Kazuki Y, Katoh M, Inoue T. , Learned Journal , The Multiple Authorship , English

• Toward Gene and Cell Therapies Employing Human Artificial Chromosomes in Conjunction with Stem Cells. , Uno N., Kazuki Y, Oshimura M. , Clon. Transgen. , OMICS Publishing Group , vol.3 (122) , 2014 , Uno N., Kazuki Y, Oshimura M. , Learned Journal , The Multiple Authorship , English

• New Vectors for Gene Delivery: Human and Mouse Artificial Chromosomes. , Oshimur M., Kazuki Y. , Iida Y., Uno N. , eLS. , John Wiley & Sons, Ltd. All. , 2013 , Oshimur M., Kazuki Y. , Iida Y., Uno N. , Learned Journal , The Multiple Authorship , English

• Human Artificial Chromosomes for Gene Delivery and the Development of Animal Models. , Kazuki Y, Oshimura M. , Mol Ther. , Nature Publishing Group , vol.19 (9) (p.1591 - 1601) , 2011.09 , Kazuki Y, Oshimura M. , Learned Journal , The Multiple Authorship , English

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Research Achievement (Book)

• MOLECULAR FARMING , Ishida I , Tomizuka K , Kuroiwa Y , Yoshida H , Shinohara T , Kazuki Y , Oshimura M , OECD/INRA , 2000.09The Book (the science book) , The Multiple Authorship , Allotment Writing , English

Updated on 2022/12/13