1 - 20 of about 72
Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy. , Beneditti Sara, Uno Narumi, Hoshiya Hidetoshi, Ragazzi Martina, Ferrari Giulia, Kazuki Yasuhiro, Katoh Motonobu, Kazuki Kanako, Oshimura Mitsuo, Tedesco Francesco Saverio,他 , EMBO Molecular Medicine , vol.10 (2) (p.254 - 275) , 2017.12 , There is Review , The Multiple Authorship , English
Gender difference of hepatic and intestinal CYP3A4 in CYP3A-humanized mice generated by a human chromosome-engineering technique. , Kobayashi Kaoru, Abe Chisato, Endo Mika, Kazuki Yasuhiro, Oshimura Mitsuo, Chiba Kan , Drug Metab Lett. , vol.11 (1) (p.60 - 67) , 2017.11 , There is Review , The Multiple Authorship , English
Modification of single-nucleotide polymorphism in a fully humanized CYP3A mouse by genome editing technology. , Abe Satoshi, Kazuki Yasuhiro,他 , Sci Rep. , vol.7 (1) , 2017.11 , There is Review , The Multiple Authorship , English
Establishment of a novel hepatocyte model that expresses four cytochrome P450 genes stably via mammalian-derived artificial chromosome for pharmacokinetics and toxicity studies. , Satoh Daisuke, Iwado Satoru, Abe Satoshi, Kazuki Kanako, Wakuri Shinobu, Oshimura Mitsuo, Kazuki Yasuhiro , PLoS One. , vol.12 (10) , 2017.10 , There is Review , The Multiple Authorship , English
Transfer of a Mouse Artificial Chromosome into Spermatogonial Stem Cells Generates Transchromosomic Mice. , Shinohara Takashi, Kazuki Yasuhiro,他 , Stem Cell Reports. , vol.9 (4) , 2017.10 , There is Review , The Multiple Authorship , English
CRISPR/Cas9-induced transgene insertion and telomere-associated truncation of a single human chromosome for chromosome engineering in CHO and A9 cells. , Uno Narumi, Hiramatsu Kei, Uno Katsuhiro, Komoto Shinya, Kazuki Yasuhiro, Oshimura Mitsuo , Sci Rep. , vol.7 (1) , 2017.10 , There is Review , The Multiple Authorship , English
Correlation between luminescence intensity and cytotoxicity in cell-based cytotoxicity assay using luciferase. , Wakuri Shinobu, Yanmakage K, Kazuki Yasuhiro, Kazuki Kanako, Oshimura Mitsuo, Aburatani S, Yasunaga Masu, Nakajima Yoshihiro , Anal Biochem. , vol.522 (p.18 - 29) , 2017.04 , There is Review , The Multiple Authorship , English
Maintenance and Function of a Plant Chromosome in Human Cells. , Wada Naoki, Kazuki Kanako, Inoue Toshiaki, Fukui Kiichi, Ohimura Mitsuo, Kazuki Yasuhiro , ACS Synth Biol. , vol.6 (2) (p.301 - 310) , 2017.02 , There is Review , The Multiple Authorship , English
Development of Caco-2 cells co-expressing CYP3A4 and NADPH-cytochrome P450 reductase using a human artificial chromosome for the prediction of intestinal extraction ratio of CYP3A4 substrates. , Takenaka Toru, Harada Naomoto, Kuze Jiro, Chiba Masato, Iwao Takahiro, Matsunaga Tamihide, Abe Satoshi, Oshimura Mitsuo, Kazuki Yasuhiro , Drug Metab Pharmacokinet. , vol.32 (1) (p.61 - 68) , 2017.02 , There is Review , The Multiple Authorship , English
Multiple expression cassette exchange via TP901-1, R4, and Bxb1 integrase systems on a mouse artificial chromosome. , Tomimatsu Kosuke, Kokura Kenji, Nishida Tadashi, Yoshimura Yuki, Kazuki Yasuhiro, Narita Masashi, Oshimura Mitsuo, Ohbayashi Tetsuya , FEBS Open Bio. , vol.7 (3) (p.306 - 317) , 2017.01 , There is Review , The Multiple Authorship , English
Induction of human cytochrome P450 3A enzymes in cultured placental cells by thalidomide and relevance to bioactivation and toxicity. , Murayama Norie, Kazuki Yasuhiro, Satoh Daisuke, Arata Kazuya, Harada Tasuku, Shibata Norio, Peter Guengerich, Yamazaki Hiroshi , J Toxicol Sci. , vol.42 (3) (p.343 - 348) , 2017 , There is Review , The Multiple Authorship , English
Thalidomide-induced limb abnormalities in a humanized CYP3A mouse model. , Kazuki Y, Akita M, Kobayashi K, Osaki M, Satoh D, Ohta R, Abe S, Takehara S, Kazuki K, Yamazaki H, Kamataki T, Oshimura M. , Sci Rep. , 2016.02 , There is Review , The Multiple Authorship , English
Dynamics of epigenetic regulation at the single-cell level. , Bintu L, Yong J, Antebi YE, McCue K, Kazuki Y, Uno N, Oshimura M, Elowitz MB. , Science. , vol.351 (6274) (p.720 - 724) , 2016.02 , There is Review , The Multiple Authorship , English
Murine Cyp3a knockout chimeric mice with humanized liver: prediction of the metabolic profile of nefazodone in humans. , Nakada N, Kawamura A, Kamimura H, Sato K, Kazuki Y, Kakuni M, Ohbuchi M, Kato K, Tateno C, Oshimura M, Usui T. , Biopharm Drug Dispos. , vol.37 (1) (p.3 - 14) , 2016.01 , There is Review , The Multiple Authorship , English
Development of a High-Sensitivity Quantitation Method for Arginine Vasopressin by High-Performance Liquid Chromatography Tandem Mass Spectrometry, and Comparison with Quantitative Values by Radioimmunoassay. , Tsukazaki Y, Senda N, Kubo K, Yamada S, Kugoh H, Kazuki Y, Oshimura M. , Anal Sci. , vol.32 (2) (p.153 - 159) , 2016 , There is Review , The Multiple Authorship , English
Development of a Safeguard System Using an Episomal Mammalian Artificial Chromosome for Gene and Cell Therapy. , Uno N, Uno K, Komoto S, Suzuki T, Hiratsuka M, Osaki M, Kazuki Y, Oshimura M. , Mol Ther Nucleic Acids. , 2015.12 , There is Review , The Multiple Authorship , English
Mouse embryonic stem cells with a multi-integrase mouse artificial chromosome for transchromosomic mouse generation. , Yoshimura Y, Nakamura K, Endo T, Kajitani N, Kazuki K, Kazuki Y, Kugoh H, Oshimura M, Ohbayashi T. , Transgenic Res. , vol.24 (4) (p.717 - 727) , 2015.08 , There is Review , The Multiple Authorship , English
Development of Murine Cyp3a Knockout Chimeric Mice with Humanized Liver. , Kato K, Ohbuchi M, Hamamura S, Ohshita H, Kazuki Y, Oshimura M, Sato K, Nakada N, Kawamura A, Usui T, Kamimura H, Tateno C. , Drug Metab Dispos. , vol.43 (8) (p.1208 - 1217) , 2015.08 , There is Review , The Multiple Authorship , English
Retargeting of microcell fusion towards recipient cell-oriented transfer of human artificial chromosome. , Hiratsuka M, Ueda K, Uno N, Uno K, Fukuhara S, Kurosaki H, Takehara S, Osaki M, Kazuki Y, Kurosawa Y, Nakamura T, Katoh M, Oshimura M. , BMC Biotechnol. , 2015.06 , There is Review , The Multiple Authorship , English
Recurrent Micronucleation through Cell Cycle Progression in the Presence of Microtubule Inhibitors. , Nakayama Y, Uno N, Uno K, Mizoguchi Y, Komoto S, Kazuki Y, Nanba E, Inoue T, Oshimura M. , Cell Struct Funct. , vol.40 (1) (p.51 - 59) , 2015.03 , There is Review , The Multiple Authorship , English